Fox received a Ph.D. in Theoretical Physics from Cambridge University, where he was Senior Wrangler. He is now a Professor at the Biocomplexity Institute & Initiative and Computer Science Department at the University of Virginia. He previously held positions at Caltech, Syracuse University, Florida State University, and Indiana University. After being a postdoc at the Institute for Advanced Study at Princeton, Lawrence Berkeley Laboratory, and Peterhouse College Cambridge. He has supervised the Ph.D. of 77 students. He has an index of 87 with over 42,000 citations. He received the High-Performance Parallel and Distributed Computing (HPDC) Achievement Award and the ACM - IEEE CS Ken Kennedy Award for Foundational contributions to parallel computing in 2019. He is a Fellow of APS (Physics) and ACM (Computing) and works on the interdisciplinary interface between computing and applications. His current focus is on algorithms and software systems needed for the AI for Science revolution.